S2Ep18: Evolution of Anatomic and Clinical Pathology in the Last Century

Anatomic pathology has evolved dramatically in the last 100 years, moving from an entirely subjective practice to a standardized, evidence-based discipline.  

Who were the pioneers in developing this modern approach? How have testing processes and laboratory technology changed over time? And what can we learn from the last century of anatomic pathology to help us move the profession forward? 

On this episode of Inside the Lab, our hosts Ms. Kelly Swails and Dr. Dan Milner are joined by Dr. Sanjay Mukhopadhyay, MD, Director of Pulmonary Pathology at the Cleveland Clinic and Associate Editor of the American Journal of Clinical Pathology, and Dr. William Schreiber, MD, MASCP, Professor in the Department of Pathology and Lab Medicine at the University of British Columbia and Clinical Director of Chemistry at LifeLabs, to discuss the history of pathology and laboratory medicine. 

Our panelists explain who and what inspired the marked increase in scientific rigor in our profession and explore how the role of the pathologist has changed over time. They speak to how instrumentation has evolved since 1922, describing the diversity of technology in the lab today and the many iterations of molecular testing in surgical pathology and the clinical lab. Listen in for  insight on promoting diversity of thought in pathology and laboratory medicine and get their predictions around the disruptive innovation coming to anatomic pathology in the next 100 years.

Topics Covered  
· Pioneers in developing modern anatomic pathology’s standardized, evidence-based approach
· How immunohistochemistry and molecular pathology led to a marked increase in scientific rigor in laboratory medicine
· How the role of the pathologist has changed over time to be directly involved in patient care decisions 
· How instrumentation has changed in the clinical lab over the last 100 years 
· The diversity of technology in the laboratory today and how automation benefits patients
· The evolution of molecular testing in surgical pathology and laboratory medicine and how it’s impacted microbiology, genetics and cancer diagnoses
· How molecular testing has evolved from conventional cytogenetics to FISH testing to PCR testing (and now to next-generation sequencing)
· Where the laboratory has been ahead of the curve on diversity and where we have room for improvement
· Dr. Mukhopadhyay’s and Dr. Schreiber’s predictions around AI and non-invasive diagnostics in future of pathology and laboratory medicine
· Transformative vs. disruptive innovation and why anatomic pathology is ripe for disruption 

Connect with ASCP
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Connect with Dr. Mukhopadhyay
Dr. Mukhopadhyay on Twitter
Dr. Mukhopadhyay on LinkedIn 

Connect with Dr. Schreiber
Dr. Schreiber at the University of British Columbia
Dr. Schreiber at LifeLabs 

Connect with Ms. Swails & Dr. Milner
Ms. Swails on Twitter
Dr. Milner on Twitter

Resources 
Inside the Lab in the ASCP Store